3. What is meant by the term pharmacokinetics? How is drug dosing dependent on a drug’s dose-response curve and what factors affect this curve?

1. What are the different factors that can affect drug disposition?
2. How are therapeutic drugs absorbed, distributed, metabolized, and excreted? What role does cytochrome P 450 play in drug metabolism?
3. What is meant by the term pharmacokinetics? How is drug dosing dependent on a drug’s dose-response curve and what factors affect this curve?
4. Which therapeutic parent drugs have active metabolites that must be monitored? Name the metabolites.

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